scleroderma

Ka nānā 'ana o ka scleroderma

ʻO Scleroderma kahi maʻi pili autoimmune a me ka maʻi rumatika e hoʻoulu ai i ka ʻili a me nā wahi ʻē aʻe o ke kino. Ke manaʻo ka pane ʻana o ka immune i nā ʻiʻo ua pōʻino lākou, hoʻomake ia a hoʻohua nui ke kino i ka collagen, e alakaʻi ana i ka scleroderma. ʻO ka nui o ka collagen i loko o ka ʻili a me nā ʻiʻo ʻē aʻe e hopena i nā ʻāpana o ka ʻili paʻa a paʻakikī. Hoʻopilikia ka Scleroderma i nā ʻōnaehana he nui i kou kino. ʻO nā wehewehe ma lalo nei e kōkua iā ʻoe e hoʻomaopopo maikaʻi i ka hopena o ka maʻi i kēlā me kēia ʻōnaehana.

• ʻO ka maʻi pili i ke kino he maʻi ia e pili ana i nā ʻiʻo e like me ka ʻili, nā aʻa, a me ka cartilage. Kākoʻo, pale, a hāʻawi ka ʻiʻo pili i ke kino i nā ʻiʻo a me nā ʻāpana ʻē aʻe.
• Loaʻa nā maʻi autoimmune i ka wā e hoʻouka ai ka ʻōnaehana pale, ka mea maʻamau i ka pale ʻana i ke kino mai ka maʻi a me nā maʻi, e hoʻouka i kāna mau kiko ponoʻī.
• ʻO nā maʻi Rheumatic e pili ana i kahi hui o nā kūlana i hōʻike ʻia e ka mumū a i ʻole ka ʻeha i loko o nā ʻiʻo, nā hono a i ʻole ka ʻiʻo fibrous.

ʻElua ʻano nui o ka scleroderma:

• Pili wale ka scleroderma kūloko i ka ʻili a me nā hale ma lalo pono o ka ʻili.
• ʻO ka systemic scleroderma, i kapa ʻia ʻo systemic sclerosis, pili i nā ʻōnaehana kino he nui. He ʻano koʻikoʻi kēia o ka scleroderma hiki ke hōʻino i nā kīʻaha koko a me nā ʻāpana o loko e like me ka naʻau, nā māmā, a me nā puʻupaʻa.

ʻAʻohe lāʻau lapaʻau no ka scleroderma. ʻO ka pahuhopu o ka lāʻau lapaʻau e hoʻomaha i nā hōʻailona a hoʻopau i ka holomua o ka maʻi. He mea nui ka ʻike mua a me ka nānā mau ʻana.

He aha ka hana me ka scleroderma?

ʻAʻole ʻike ʻia ke kumu o ka scleroderma. Eia nō naʻe, manaʻo ka poʻe noiʻi ua ʻoi aku ka nui o ka ʻōnaehana pale a hoʻoulu i ka mumū a me ka hōʻino ʻana i nā cell e pili ana i nā kīʻaha koko. ʻO kēia ka mea e hoʻohua ai i ka nui o ka collagen a me nā protein ʻē aʻe. ʻOi aku ka lōʻihi o ka ola ʻana o nā fibroblasts ma mua o ka mea maʻamau, e hoʻoulu ai i ka collagen i ka ʻili a me nā ʻāpana ʻē aʻe, e alakaʻi ana i nā hōʻailona a me nā hōʻailona o ka scleroderma.

ʻO wai ka maʻi scleroderma?

Hiki i kekahi ke loaʻa i ka scleroderma; akā naʻe, ʻoi aku ka nui o ka maʻi o kekahi mau hui. Hiki i kēia mau mea ke hoʻopilikia i kou pilikia.

• Ka wahine. ʻOi aku ka maʻamau o ka scleroderma i nā wahine ma mua o nā kāne.
• Makahiki. ʻIke pinepine ʻia ka maʻi ma waena o nā makahiki 30 a me 50 a ʻoi aku ka maʻamau i nā pākeke ma mua o nā keiki.
• Lahui. Hiki i ka Scleroderma ke hoʻopilikia i nā kānaka o nā lāhui a me nā lāhui āpau, akā hiki i ka maʻi ke hoʻopilikia i nā ʻAmelika ʻAmelika. ʻo kahi laʻana: 
  • ʻOi aku ka maʻi i nā ʻAmelika ʻAmelika ma mua o nā ʻAmelika ʻEulopa.
  • Hoʻokumu mua nā ʻAmelika ʻAmelika me ka scleroderma i ka maʻi i hoʻohālikelike ʻia me nā hui ʻē aʻe.
  • ʻOi aku ka maʻalahi o ka poʻe ʻAmelika ʻAmelika i nā ʻili ʻili a me nā maʻi ʻulaʻula e like me nā hui ʻē aʻe.

ʻO nā ʻano scleroderma

• Hoʻopilikia ka scleroderma kūloko i ka ʻili a me nā ʻiʻo lalo a loaʻa pinepine me hoʻokahi a ʻelua paha o kēia mau ʻano:
  • ʻO nā ʻāpana Morpheus a i ʻole scleroderma, hiki i ka hapalua ʻīniha a ʻoi aku paha ke anawaena.
  • ʻO Linear scleroderma ka wā e ulu ai ka mānoanoa o ka scleroderma ma kahi laina. Hohola maʻa i ka lima a i ʻole ka wāwae, akā i kekahi manawa palahalaha ma ka lae a me ka maka.
• ʻO ka systemic scleroderma, i kapa ʻia ʻo systemic sclerosis, pili i ka ʻili, nā ʻiʻo, nā kīʻaha koko, a me nā ʻano nui. Hoʻokaʻawale pinepine nā kauka i ka scleroderma systemic i ʻelua ʻano:
  • ʻO ka scleroderma ʻili liʻiliʻi e ulu mālie a pili i ka ʻili o nā manamana lima, nā lima, ka maka, nā lima, a me nā wāwae ma lalo o nā kuli.
  • ʻO ka maʻi scleroderma ʻili ākea e ulu wikiwiki a hoʻomaka me nā manamana lima a me nā manamana wāwae, akā palahalaha ma waho o nā kuʻekuʻe a me nā kuli a hiki i nā poʻohiwi, ka ʻōpala, a me nā pūhaka. ʻOi aku ka nui o ka pōʻino o kēia ʻano i nā kino o loko.  

Nā hōʻailona o ka scleroderma

ʻOkoʻa nā hōʻailona o ka scleroderma mai kēlā me kēia kanaka ma muli o ke ʻano o ka scleroderma.

ʻO ka scleroderma kūloko ke kumu maʻamau i nā ʻāpana o ka ʻili mānoanoa a paʻakikī i kekahi o nā ʻano ʻelua.

• Hoʻomaka ka Morphea i ka mānoanoa o nā ʻāpana ʻili i loko o nā ʻāpana paʻakikī, ʻano oval. He melemele paha kēia mau wahi, ʻano waxy i hoʻopuni ʻia e ka ʻaoʻao ʻulaʻula a ʻeha paha. Hiki ke waiho ʻia nā kiko ma kekahi wahi a i ʻole e laha i nā wahi ʻē aʻe o ka ʻili. E lilo ana ka maʻi i mea ʻole i ka wā lōʻihi, akā loaʻa paha iā ʻoe nā ʻāpana ʻeleʻele o ka ʻili. Ke ulu nei kekahi poʻe i ka luhi (manaʻo luhi).
• I ka scleroderma linear, holo nā laina o ka ʻili mānoanoa a ʻulaʻula paha ma ka lima, ka wāwae, a me ka lae.

ʻO ka systemic scleroderma, ʻike ʻia hoʻi ʻo ka systemic sclerosis, hiki ke ulu wikiwiki a mālie a hiki ke hoʻopilikia i nā pilikia ʻaʻole wale i ka ʻili akā me nā ʻāpana o loko. Nui nā poʻe me kēia ʻano scleroderma e ʻike i ka luhi.

• Hoʻoulu mālie ʻia ka scleroderma cutaneous kūloko a pili pinepine i ka ʻili ma nā manamana lima, nā lima, ka maka, nā lima mua, a me nā wāwae ma lalo o nā kuli. Hiki iā ia ke hoʻopilikia i nā kīʻaha koko a me ka esophagus. ʻO ke ʻano liʻiliʻi ke komo i loko o ka visceral akā ʻoi aku ka maʻalahi ma mua o ke ʻano diffuse. Loaʻa i ka poʻe me ka scleroderma cutaneous localized nā hōʻailona āpau a i ʻole kekahi o nā hōʻailona, ​​​​i kapa ʻia e kekahi mau kauka ʻo CREST, ʻo ia hoʻi kēia mau hōʻailona:
  • ʻO Calcification, ka hoʻokumu ʻana o nā waihona calcium i loko o nā ʻiʻo pili, hiki ke ʻike ʻia e ka hoʻokolokolo X-ray.
  • ʻO Raynaud's phenomena, kahi maʻi i ʻokoʻa ai nā kīʻaha koko liʻiliʻi ma nā lima a me nā wāwae i ka pane ʻana i ke anu a i ʻole ka hopohopo, e hoʻololi ai nā manamana lima a me nā manamana wāwae (keʻokeʻo, uliuli, a ʻulaʻula paha).
  • ʻO ka esophageal dysfunction, kahi e pili ana i ka hana ʻino o ka esophagus (ka paipu e hoʻopili ai i ka ʻāʻī a me ka ʻōpū) i hana ʻia i ka wā e nalowale ai nā ʻiʻo maʻemaʻe o ka esophagus.
  • ʻO Sclerodactyly ka ʻili mānoanoa a paʻapū ma nā manamana lima ma muli o ka waiho ʻana o ke kolagen nui i nā papa o ka ʻili.
  • ʻO Telangiectasia, he maʻi ma muli o ka pehu ʻana o nā kīʻaha koko liʻiliʻi e ʻike ʻia ai nā kiko ʻulaʻula liʻiliʻi ma nā lima a me ka maka.
• Hiki koke mai ka scleroderma cutaneous diffuse, maʻamau me ka mānoanoa o ka ʻili ma nā manamana lima a me nā manamana wāwae. Hoʻonui ka mānoanoa o ka ʻili i ke koena o ke kino ma luna o nā kuʻekuʻe a me nā kuli. Hiki i kēia ʻano ke hōʻino i kou mau kino i loko e like me:
  • Ma nā wahi a pau o kāu ʻōnaehana digestive.
  • kou mau māmā.
  • kou mau puʻupaʻa.
  • ʻO kou puʻuwai.

ʻOiai ua kapa ʻia ʻo CREST ma ke ʻano he scleroderma kūloko, loaʻa paha i nā poʻe me ka scleroderma diffuse nā hōʻailona o CREST.

Nā kumu o ka scleroderma

ʻAʻole ʻike ka poʻe noiʻi i ke kumu kūpono o ka scleroderma, akā manaʻo lākou he nui nā kumu i hoʻopili i ke ʻano:

• haku mele. Hiki i nā genes ke hoʻonui i ka likelike o kekahi poʻe e ulu ana i ka scleroderma a pāʻani i kahi kuleana i ka hoʻoholo ʻana i ke ʻano o ka scleroderma i loaʻa iā lākou. ʻAʻole hiki iā ʻoe ke hoʻoili i ka maʻi, ʻaʻole hoʻi i hoʻoili ʻia mai ka makua i ke keiki e like me kekahi mau maʻi genetic. Eia naʻe, ʻoi aku ka nui o ka pilikia o nā ʻohana pili o ka poʻe me ka scleroderma ma mua o ka lehulehu.
• Kaiapuni. Manaʻo ka poʻe noiʻi ʻo ka ʻike ʻana i kekahi mau mea kaiapuni, e like me nā maʻi maʻi a i ʻole nā ​​​​kemika, hiki ke kumu i ka scleroderma.
• Hoʻololi ka ʻōnaehana pale. ʻO ka hana ʻino ʻole a i ʻole nā ​​​​hana ʻeha i loko o kou kino ke kumu i nā loli kelepona e hoʻoulu ai i ka nui o ka collagen.
• Hormonal. Loaʻa pinepine nā wahine i nā ʻano scleroderma ma mua o nā kāne. Manaʻo ka poʻe noiʻi e pili ana ka ʻokoʻa hormonal ma waena o nā wahine a me nā kāne i ka maʻi.